Clusterin is a multifunctional glycoprotein that has attracted considerable attention in oncology due to its paradoxical roles in cancer progression and therapeutic resistance. It exists in distinct ...

This story is part 9 of an occasional series on the current progression in Regenerative Medicine. In 1999, I defined regenerative medicine as the collection of interventions that restore to normal ...

In a new study published in Neuron titled “CLU alleviates Alzheimer’s disease-relevant processes by modulating astrocyte reactivity and microglia-dependent synaptic density,” researchers from Mass ...

Signaling through the CD33 receptor counteracts the known beneficial microglial responses to plaques, while clusterin is thought to promote Aβ aggregation. Up until now, these two AD risk factors were ...

The clinical diagnostic industry is on the verge of a recombinant protein revolution. Recombinants have been available for decades and have served some sectors of diagnostics quite well, but they have ...