The primary role of Mouse Genetics Core Facility (MGCF) is to facilitate the use of mouse molecular genetics at MSK for in vivo studies of gene functions germane to cancer. Relevant fields in which ...

Developing treatments aimed at the causes of diseases such as cancer, infections and metabolic, autoimmune and psychiatric disorders requires knowledge of the underlying biological mechanisms. Such ...

After 5-10 generations of inbreeding, mouse colonies should be “refreshed”, to remove or prevent genetic drift accumulation in the colony. Several methods to refresh the genetic background may include ...